The microneedling fractional micro delivery provides unparalleled collagen induction via fragmented delivery of needles into the epidermis and dermis. These micro injuries to the skin encourage and harness the power of the body’s innate ability to re-grow and repair the skin through the physiology of collagen induction. The before and afters are typical of a series of treatments where patients experienced six treatments over the space of six months. Each treatment is done four weeks apart.

Microneedling offers a solution for all skin conditions that clients might seek treatment for: wrinkles and fine lines, Acne scarring, stretch marks, wound healing stimulation, and skin tightening, lifting and rejuvenation. This means you can offer a broader range of treatments for your clients. Microneedling treatments complement other treatment options already offering clients, chemical peels, IPL, Micro-dermabrasion and laser skin tightening. This will greatly increase their effectiveness.



The microneedling fractional micro delivery provides unparalleled collagen induction via fragmented delivery of needles into the epidermis and dermis. These micro injuries to the skin encourage and harness the power of the body’s innate ability to re-grow and repair the skin through the physiology of collagen induction. The microneedling controlled precision allows for the three phases of CIT mechanics of new collagen growth to occur. The first phase begins with the release of the bodies growth factors and the further cascade of new epidermal growth, fibroblast chemo-taxis, fibroblast proliferation and matrix production. This proliferation of the body’s tissue continues to release growth factors from fibroblasts, keratinocytes and monocytes culminating in the second of three phases of CIT mechanics where collagen III, IV and I, elastin, proteoglycans, GAG’s and angiogenesis occur. The last phase of CIT and the Cryo Pen treatment results in the tissue remodeling process where the skins vascular matrix matures and skin tightening as well as new collagen can be seen. The body’s ability to remodel and heal itself is at the heart of this amazing product and because the process never involves heat or thermal energy or other chemicals or unnecessary trauma, the skin can quickly heal with almost zero downtime.

  • Microneedling

    What makes microneedling Different:

    The closest technology to the microneedling is a fractional laser.  A fractional laser “drills holes” in the skin to create a wound healing response and leaves normal tissue around the holes to be a reservoir for fibroblasts and stem cells to migrate into the holes.  Fractional radio frequency devices work on a similar principle and have many of the same side effects as fractional lasers (Yeung et al., 2012).  Microneedling also makes holes in the skin to create a wound healing response and leaves normal tissue around the holes.  These technologies have similar results, but achieve them in very different ways, and result in very different side effects profiles.  The laser uses light to char and obliterate epidermis to produce small pits which vary in diameter and depth, depending on the laser type (Erbium, YAG, CO2; nonablative vs ablative) and manufacturer.  Microneedling produces reproducible and consistent holes in the skin.

    Side effects differ between technologies.  Most fractional lasers leave erythema and edema up to 48 hours after treatment.  Resultant down time is approximately 3-4 days for fractional laser treatments (Gold, 2010). Microneedling treatments result in erythema without edema for about 24 hours. Microneedling has none of the side effects specific to fractional lasers, such as:

    • Pain (higher in dark skined patients (Mahmoud et al., 2010)
    • Persistent erythema (Gold 2010)
    • Infections (viral and bacterial).  Facial herpes reported in 10.6% of patients in spite of antiviral prophylaxis (Naouri et al., 2011)
    • Postinflammatory hyperpigmentation in up to 18% (Vaiyavatjamai and Wattanakrai, 2011; Chan et al., 2010; Mahmoud et al., 2010; Yeung et al., 2012)
    • Postinflammatory hypopigmentation – seen in patients up to two years after a laser treatment. Occurs in up to 20% of patients with photo-aged skin (Gold 2001).

    Light based therapy is not for all skin types.  For example, the indications for use cleared by the FDA may put limits on the skin types that may be treated with a fractional laser.  For example, the indications for use may prohibit the use of the laser on Fitzpatrick 4, 5 , and 6 (darker skin colors), for example: “The EXELO2 with the fractional scanning unit is indicated for ablative skin resurfacing in people with skin types 1, 2 or 3 based on Fitzpatrick skin type scale.” K090639.  The fractional holes “drilled” by the laser are a function of skin type, skin thickness, and vascularity.  A major complication from light based therapy includes Postinflamatory Hyperpigmentation. Microneedling is not affected by skin type as it does not rely on skin color to turn light into heat.


    What causes acne scars?

    Scars are areas of fibrous tissue (fibrosis) that replace normal skin after injury. A scar results from the biological process of wound repair in the skin and other tissues of the body. With the exception of very minor lesions, every wound (e.g. after accident, disease, surgery) results in some degree of scarring. Scar tissue is the same protein (collagen) as the tissue that it replaces, but the fiber composition of the protein is different. Instead of a nice “basket weave” formation of fibers, the collagen in scar tissue is aligned in a single direction resulting in a pronounced and thicker appearance. Acne treatments for most are long term and can result in scarring. There are multiple causes of acne including hormone dysfunction, allergies, environmental factors and nutrition deficiencies. Acne scars result after skin follicles become blocked by excessive oils and the physiology of keratin and old skin cells trigger an inflammatory response reaction. The skin will attempt to heal and the scar tissue results as the collagen becomes deformed and thickens. Acne scars are categorized as being “ice- pick”, “rolling” or “boxcar.”

    How to treat acne scars/ surgical scars.

    The microneedling treatment can provide drastic results improving the appearances of the scars. The micro needles of the microneedling create new collagen and elastin to be generated and deposited called collagenesis, however the added benefit of new capillary growth is also a result which can improve blood supply to the area which helps create healthier existing skin as well as provide a healthy foundation for the new skin. The physical nature of “skin-needling” breaks up this fibrous and uneven scar tissue and stimulates the growth of new tissue. Currently there are ablative and non-ablative treatments offered which can damage the epidermis and evaporate the skin leading to thinner epidermis problems. The microneedling keeps the epidermis integrity full intact while treating the area which quickens healing time and causes less pain.

    How many treatments?

    Your skin care professional should consult on medical treatment. While each patient is different and conditions will vary, the typical treatment regimen will consist of 5-6 treatments.

    Acne Scars: Over 90% of adolescents have acne and 1% of the population have acne scars.

    Why Acne Scars?  Acne scars are created by the wound healing process occurring after the acute process of inflammation, follicular rupture and perifollicular abscess formation.

    Types of Acne Scars.  The resulting acne scars may be atrophic or hypertrophic (Fabbrocini et al., 2010).  Approximately 80% of scars are atrophic associated with a net loss of collagen during the matrix remodeling process.  A minority of scars are hypertrophic or have keloid formation.  Atrophic scars are classified as:

    Ice pick (70%) – These are the narrow < 2mm punctiform depressions with a “V” cross-section.

    Boxcar (20%) – These are round or oval scars with well-established vertical edges with a wide base and a “U” cross-section.

    Rolling scars (10%) – These wide > 4 mm scars have an “M” cross-section and give an undulating appearance to the skin.

    The microneedling is a convenient and effective way of performing needle dermabrasion.

    The microneedling adjustable needles penetrate a controlled depth into the dermis.  The dermis develops multiple microbruises, which start a cascade of growth factor release and collagen production.  Punch biopsy histology demonstrates thickening of the skin with dramatic increases in new collagen and elastin fibers (Fabbrocini et al., 2010).  As collagen is deposited, the skin texture improves.  Results are initially seen in six weeks and full effect will take three months to develop.

    Severity grade of rolling scars has been shown to be statistically reduced in a clinically meaningful fashion after two sessions of needle dermabrasion (Fabbrocini et al., 2009).  Importantly, there was no sign of hyperpigmentation in the 32 patients studied.


    A wrinkle is a fold, ridge or crease in the skin. Skin wrinkles typically appear as a result of the aging processes resulting in a thinning of the epidermal layers of the skin as they lose the ability to retain moisture. Wrinkling in the skin is caused by habitual facial expressions, aging, sun damage, smoking, poor tion, and various other factors. Depletion of water in the body, as occurs with detion, can also cause this puckering of the skin. The dermal layer of the skin thins and produces less and less collagen over time. Underlying the dermal layer of the skin is the subcutaneous layer which consists of fat cells which shrink with age and become less able to support the upper layers of the skin which make wrinkles even more noticeable.

    How can you prevent wrinkles?

    Because of the degradation of the skin over time, the required regimen for treatment is a preventative protocol. Microneedling promotes a process of new skin growth through the science of Collagen Induction Therapy (CIT). The most effective way to stimulate or “Induce” new skin is by micro-needling with the microneedling vertical stamping method. This new stimulation can be done quickly and easily while keeping the epidermis intact and down-time to a minimum.

    How many microneedling treatments are needed?

    Your medical professional can consult you on a prescribed treatment. Skin conditions are different as well as the age of each patient. 2-3 aggressive Derma Pen treatments will provide a noticeable difference, however 5-6 Derma Pen treatments will show the most dramatic results. It is important to work with your practitioner on what treatment specifics to observe. Once the skin condition has the desired effects, it is important to maintain collagen stimulation by returning to your practitioner or performing a new Derma Pen treatment every 12-24 weeks.

    Stretch Marks

    What causes stretch marks?

    According to Wikipedia, stretch marks or striae (singular stria), as they are called in dermatology, are a form of scarring on the skin with an off-color hue. They are caused by tearing of the dermis, and over time can diminish but not disappear completely. Stretch marks are often the result of the rapid stretching of the skin associated with rapid growth. Stretch marks may also be influenced by hormonal changes associated with puberty, pregnancy, muscle building, hormone replacement therapy for transsexuals, etc. Medical terminology for these kinds of markings includes striae atrophicae, vergetures, stria distensae, striae cutis distensae, striae gravidarum (in cases where it is caused by pregnancy), lineae atrophicae, linea albicante, or simply striae.

    How can they be treated?

    Various treatments are available for the purpose of improving the appearance of existing stretch marks, including laser treatments, dermabrasion, and prescription retinoids.[citation needed] Some cream manufacturers claim the best results are achieved on recent stretch marks; however, few studies exist to support these claims. The use of the microneedling uses the bodies natural solution for unsightly stretch marks. New collagen growth and stimulation is more effective for reducing and fading stretch marks. The microneedling does this through Collagen Induction Therapy (CIT).

    The microneedling device allows for appropriate treatment needle depth to activate the cascade of fibroblast and growth hormone steps to generate more skin, collagen and elastin for smooth and healthy colored skin. The skin of the epidermis effectively thickens and noticeable smoother and evening of stretch marks is the result.

    How many treatments are needed?

    Your medical professional can consult you on a prescribed treatment. Most patients see a noticeable difference in just one treatment however 5-6 treatments may be necessary. After 5-6 treatments striae improvement is noticeable with improved texture and appearance of mature, white striae in skin types I-IV. Four weeks between treatments is necessary to allow the bodies natural skin cycle to complete before another treatment should be performed.

    Burn Scar or Wound

    What causes a burn scar or wound?

    A burn is a type of injury to flesh caused by heat, electricity, chemicals, light, radiation or friction. Most burns affect only the skin (epidermal tissue and dermis). Managing burn injuries properly is important because they are common, painful and can result in disfiguring and disabling scarring, Burn scar contracture refers to the tightening of the skin after a second or third degree burn. When skin is burned, the surrounding skin begins to pull together, resulting in a contracture.

    How can they be treated?

    The challenge of a burn scar lies within the matrix of all the forms or categories of the scars involving hypertrophic and keloid scars and pigmentation flaws. These scars thicken over time. Burn scar therapy has been historically limited. The microneedling unique vertical stamping and depth control up to 2.5mm makes treating burn scars superior to other methods or rollering. With surgical steel integrity, the robust nature of the automated needle tip (eleven (11) needles total and sized at thirty-three guage) penetrate difficult burn scar tissue dramatically improving appearance, texture, elasticity, size and mobility.

    Treatment Regimen

    Burn scars have altered physiology than other skin conditions. Multiple treatments will be needed and vary depending on the severity of the burn scar to see desired results.

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